ESCHSCHOLTZIA Formul'ion

Eschscholtzia helps to promote relaxation mental and physical well-being, improves the quality of natural sleep.

Ingredient: 
Powder of aerian parts of eschscholtzia californica, 
Vegetable capsule, Anti agglomerant: rice bran)

Directions for use:
Take 1 to 2 capsules with a glass of water between 3 meals. Do not exceed the recommended daily dose. The use of this dietary supplement should not be a substitute for a varied, balanced diet and a healthy lifestyle. 
Keep out of reach of children.
Store cool, dry and away from light.

PROPERTIES
Eschscholtzia or California poppy is listed by the National Agency for the Safety of Medicines and Health Products on the "list of medicinal plants traditionally used". It enjoys a great reputation for its sedative, sleep-inducing, anxiolytic, antispasmodic and minor analgesic effects. It is a natural hypnotic that  acts on the one hand on sleep disorders by facilitating falling asleep, reducing nocturnal awakenings, enuresis nightmares and on the other hand on nervousness and stress, as well as psychosomatic disorders related to them, without causing any addiction.

It is also renowned for its antispasmodic properties and thus soothes pain due to colic, intestinal irritation, gallbladder. Like all plants belonging to the Papaveraceae family, eschscholtzia contains many alkaloids that are in its case, devoid of toxicity (alkaloid is the generic name of various substances, we know nearly 1000, belonging to organic chemistry of plant origin, having therapeutic or toxic properties).

Among the most important alkaloids we find in the eschschotzia the following:

• Bisnorogemonin and Norargémonine (also present in Argemone mexicana), Eschscholtzine and Californidine typical of the California poppy.
• Fumarin and Sanguinarine found in many papaveraceae (sanguinarine, celandine, argemone).
• Celerythrin, Chelidonine and Homicidonine are also present.
• Alkaloids of the aporphine group: Lauroscholtzine, Glaucine.

Eschscholtzia californica was studied in France by the team of the Pharmacognosy Laboratory of the University of Metz: Rolland A, Fleurentin J, Mortier F and their colleagues.
They showed that the aqueous or hydroalcoholic extract of the California poppy is, in mice:

They found that when the "benzodiazepine receptor site" is blocked by an antagonistic substance, the California poppy loses its sedative power, according to them the alkaloids of eschscholtzia are not the only ones responsible for the psychotropic sedative or anxiolytic activity.

In addition, in vitro, it is known that an extract of eschscholtzia:

• Is antispasmodic, perhaps because of Protopine, antispasmodic and anticholinergic.
• Slows the heart rate.

Some alkaloids are cytotoxic, antifungal, slightly anti-inflammatory. In humans, clinical trials generally confirm the sedative, somewhat hypnotic and anxiolytic power of aqueous or hydroalcoholic extracts of the California poppy. They would also seem slightly analgesic.

Rice bran is an anti-caking agent incorporated into the capsules, which ensures the fluidity of the preparation.
The composition of the capsules is vegetable.

A bit of history...
Originally from California, Escholtzia was introduced to Europe in the nineteenth century as an ornamental plant by J.F. ESCHOLTZ, a Russian botanist. The Indians used the sap of this plant for its analgesic properties, especially in case of toothache. It was not until the twentieth century that the flowers of Eschscholtzia were used for their sleeping, calming and analgesic properties.

The first alkaloids discovered were morphine in 1805 in opium, strychnine discovered in 1818 and caffeine discovered in 1819.